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WellbutrinŽ is an antidepressant that works by affecting two chemicals in the brain that are believed to help regulate your mood (dopamine and norepinephrine). SR = Sustained Release
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Common Brand Name(s)
Wellbutrin SR (Sustained Release) Tablets
Uses
Wellbutrin is a pharmaceutical prescription antidepressant
which acts directly on the brain and other nerve
cells. It is also used to treat ADHD (Attention
Deficit Disorder), Bipolar depression, chronic fatigue
syndrome, cocaine addiction, nicotine addiction,
and lower back pain. Also, aids in quitting smoking
(identical to Zyban). It is chemically unrelated
to tricyclic, tetracyclic, selective serotonin re-uptake
inhibitor, or other known antidepressant agents.
How to Use
This medication may be taken with food if stomach
upset occurs. Take doses at regularly scheduled
times each day. Do not take more or less medication
than prescribed and follow your doctor's instructions
carefully. Taking more than the recommended dose
of bupropion will increase your risk of having a
seizure. Do not stop taking this medication without
notifying your doctor. Since this drug may cause
sleeplessness at first, it is best not to take this
near bedtime. It may take 4 weeks or more before
the full effects of this medication are noticed.
Side Effects
This medication is generally well tolerated. Dry
mouth, headache, increased sweating, nausea/vomiting,
constipation, anxiety, fatigue and blurred vision
may occur. If these effects persist or worsen, notify
your doctor. Report promptly: unusual weight loss
or gain, palpitations, agitation, trouble sleeping.
Unlikely but report promptly: tremor, dizziness,
fainting, mood changes, slowed movements, difficulty
urinating, decreased sex drive, drowsiness. Very
unlikely but report promptly: seizures, mental problems,
fever, muscle aches, yellowing of the eyes or skin.
In the unlikely event you have an allergic reaction
to this drug, seek medical attention immediately.
Symptoms may include trouble breathing, rash, itching,
swelling, or severe dizziness. If you notice other
effects not listed above, contact your doctor or
pharmacist.
Precautions
Before taking bupropion, tell your doctor if you
have: history of seizures or head injury or brain
tumor, heart disease, liver or kidney disease, eating
disorder, diabetes, alcohol dependence, any allergies,
the intent to quit smoking. Because of the possibility
this drug will make you dizzy and affect coordination,
do not drive or operate machinery until you get
used to the drug's effects. Limit or avoid consumption
of alcoholic beverages; alcohol can increase your
risk of seizures. Chronic alcohol users who suddenly
stop the intake of alcohol while taking bupropion
may increase the risk of having seizures. Suddenly
stopping certain tranquilizers (e.g., diazepam,
chlordiazepoxide) is not recommended because doing
so may increase the risk of having seizures. Elderly
patients may be more sensitive to the effects of
this drug. Tell your doctor if you are pregnant
or plan to become pregnant before taking this drug.
This drug passes into breast milk. Because of the
potential risk to the infant, breast-feeding while
using this drug is not recommended. Consult your
doctor before breast-feeding.
Drug Interactions
Before taking bupropion tell your doctor of all
nonprescription and prescription medications you
may use especially: MAO inhibitors (e.g., isocarboxazid,
phenelzine, tranylcypromine, pargyline, selegiline,
linezolid, furazolidone), levodopa, ritonavir, corticosteroids
(e.g. prednisone), sedatives, adrenaline-like stimulants
(e.g., ephedrine), products containing nicotine
(e.g., patches or gum). Also report use of drugs
which might increase seizure risk (decrease seizure
threshold) such as: phenothiazines (e.g., chlorpromazine),
tricyclic antidepressants (e.g., amitriptyline),
isoniazid (INH), theophylline. Excess caffeine intake
can increase the chance of seizures with this drug.
Check all nonprescription/prescription drug labels
for caffeine. Consult your doctor or pharmacist.
A certain product used to help quit smoking contains
bupropion. Do not take that product while using
this one. Do not start or stop any medicine without
doctor or pharmacist approval.
Overdose
If overdose is suspected, contact your local poison
control center or emergency room immediately. Symptoms
of overdose may include seizures, hallucinations,
rapid heart rate, and loss of consciousness.
Notes
Do not allow anyone else to take this medication.
Missed Dose
Take any missed dose as soon as possible but not
if it is within 4 hours of the next dose. If it
is time for the next dose, skip the missed dose
and resume your regular schedule. Do not "double-up"
the dose.
Storage
Store at room temperature and keep away from moisture
and sunlight. Do not store in the bathroom.
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